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For cancer, modulating GPx4 to induce ferroptosis offers a strategy against therapy-resistant tumors, while in cardiovascular care, boosting GPx could reduce inflammation and plaque formation

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Lean Mass Vulnerability and Anabolic Suppression GLP-1RA therapy is frequently associated with reductions in lean body mass in clinical studies [40], although preclinical experiments have reported improvements in muscle function and mass under certain conditions [41,42,43]

the newly formed acylcarnitine is then exported into the cytosol via CACT