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The BMJ 2009, 338: b1807

September 1720, 2019

We found that monocyte-derived macrophages from individuals with IBD have increased sensitivity to H 2 O 2 -induced ferroptosis and this was at least partially due to decreased expression of GPx1

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It has also been reported that prostaglandin E2 (PGE2) secretion and cyclooxygenase-2 (COX-2) expression were significantly increased in colon cells exposed to toxin A either in vivo or in vitro (Kim et al., 2007)