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(21) So far researchers have stopped short of labelling glutathione deficiency as a sole cause of IBD, but they do suggest it's a likely contributing factor

"Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthase"

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[3] It is synthesized by attaching cysteine to the carboxyl group of the glutamate side chain with a gamma peptide linkage, and to glycine with a normal peptide bond

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Indeed, the measurement of serum methionine and methylmalonic acid in cases of homocysteinemia (homocystinuria) allows for a differential diagnosis of the nutritional (non-genetic) cause