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The proposed mechanism centers on modulation of the nitric oxide system: BPC-157 counteracts L-NAME-induced eNOS blockade in rat models and supports vascular sprouting through VEGFR2 internalization (Hsieh et al., J Mol Med , 2017)

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14 weeks Reduced tingling & burning for some patients 23 months Better sensation, improved balance, reduced pain 6 months+ Nerve repair and long-term function improvement Severe or long-standing neuropathy may require ongoing treatment

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Occasionally, testing may take a little longer due to laboratory workflows or operational requirements