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It disrupts the interaction between the FOXO4 transcription factor and p53, allowing researchers to analyze apoptosis signaling in senescent cells

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Mice were introduced to a large foil-lined square plastic box with the stressor of a bright overhead light

Funding This research was supported by an Operating Grant (MOP142230) from the Canadian Institutes of Health Research (WGF), and salary support was provided by the Canadian Institutes of Health Research Fellowship Award (MFE-381806) (JMW)

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Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue