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Patients on Tirzepatide 15 mg weekly lost an average of 20.9% or 48.6 lb of their body weight after 72 weeks in the Zepbound Study 1 (NCT04184622) compared to placebo patients who lost an average of 3.1% or 7.2 lb

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Timing and absorption considerations : B12 can be taken with or without food

Could enhance retinal cell entry improving intracellular delivery

- Antihipertensive agents: NSAIDs may reduce hypotensive effects including ACE inhibitors

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