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Yue He, Huazhong University of Science and Technology, China Updates Copyright 2021 Huang, Li, Feng and Chen

Subbaramaiah K, Yoshimatsu K, Scherl E, et al

McGraw-Hill / Lange rxlist.com (Actos ) Keywords Alpha-Glucosidase Inhibitors Acarbose Trade Names: Precose Drug Class: oral hypoglycemic, -glucosidase inhibitor Mechanism of Action: inhibits the activity of enzymes required to break carbohydrates down into simple sugars within the intestine Miglitol (Glyset ) is six times more potent in inhibiting sucrase than acarbose Indications: FDA approved: as adjunct therapy in type II diabetes mellitus Non-FDA approved: potentially beneficial in Type 1 diabetes

FDA approval for orforglipron in March 2026

MOTS-c has been shown to increase insulin-independent glucose uptake into skeletal muscle

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