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Studies show most patients regain part of the lost weight and see A1C drift upward within 3-6 months

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Weight Loss Speed: What Clinical Trials Show In head-to-head trials, tirzepatide participants lost approximately 22% of body weight at the highest maintenance dose, compared to 15% for semaglutide users at equivalent timepoints

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In vivo, GLP-1 has a half-life of only 23 min, preventing its therapeutic utilisation 31,32,33,34,35

Participants can also qualify if they have a BMI of 27 or higher along with an obesity-related condition, like cardiovascular or liver disease