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The Journal of Alternative and Complementary Medicine, 16 (5), 555560

The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4

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Nutrients 8 , 460 (2016)

However, peptide hormones and their mimetics are generally prohibited in-competition and out-of-competition by most anti-doping agencies