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Firstly, during pathogen infections and inflammatory responses, cytokines, toll-like receptor (TLR) ligands, and other immune mediators can stimulate self-reactive T cells, potentially triggering autoimmune responses (95)

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The AREDS and AREDS2 studies found that a specific mixvitamins C, E, zinc, copper, lutein, and zeaxanthinreduced advanced AMD progression by about 25%

Isolated SERCA2a-overexpressing cells may fail to address these broader cellular alterations and could be detrimental