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This is the biggest challenge for new exercisers on GLP-1s

GLP-1 (GLP-1R) DPP-4 T2DM

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Yuen MF, Asselah T, Jacobson IM, Brunetto MR, Janssen HLA, Takehara T, Hou JL, Kakuda TN, Lambrecht T, Beumont M, Kalmeijer R, Guinard-Azadian C, Mayer C, Jezorwski J, Verbinnen T, Lenz O, Shukla U, Biermer M, REEF-1 Study Group

While SGLT2 inhibitors like Jardiance actually provide kidney-protective benefits in many patients with diabetes, alcohol interactions can complicate their use

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These beneficial effects, in addition to metabolic improvements in glycemic control and weight reduction, provide a compelling rationale for the further study of GLP-1 RAs in non-diabetic kidney diseases like AS