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None of the secondary breast cancer subtypes reached statistical significance: HR-positive/HER2-positive (RR, 0.98

Reduce the dose by 50% and extend the titration schedule

The development and validation of robust biomarkers for polyphenol intake and metabolism are also needed to improve accuracy in such studies (127)

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Stimulant medications can also cause gastrointestinal disturbance

In another study, response to escitalopram was associated with higher plasma baseline 5-HT levels, lower baseline KYN/TRP and QA/TRP ratios, and, among remitters, a treatment-related increase in the KYNA/3-HK ratio [193]