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Ledisa is the only GLP-1 patch that combines both berberine and prebiotics, two ingredients shown to support healthy GLP-1 levels

The results indicated that patients with vitiligo had equivalent levels of GPx with the healthy controls (SMD = 0.47, 95% CI: 1.03 to 0.08, and p = 0.095) (Figure 2)

The published literature on this combination draws on the extensive individual evidence bases for both components, with the dual-pathway synergy mechanistically supported by peer-reviewed porcine and in vitro data

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