We previously described that the verapamil stimulated GSH efflux mediated by MRP1 triggers cell death of Baby Hamster Kidney cells overexpressing MRP1 after transfection with the MRP1 gene and in human small cell lung cancer H69AR cells overexpressing MRP1 after doxorubicin selection 12,15
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The influx of FFAs into the liver leads to an abnormal increase in long-chain fatty acyl-CoA and diacylglycerol (DAG), which in turn activates protein kinase C- (PKC-) (59)
turfanensis As05 with tryptophan, while it was not detected in other strains