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Participants were randomly assigned to receive either weekly injections of tirzepatide or an non-acting placebo

HFD impairs liver glutathione biosynthesis, vitamin D metabolism genes and genes associated with non-alcoholic fatty liver disease (NAFLD) Genes involved in the GSH biosynthesis pathway were significantly downregulated in the livers of mice fed an HFD compared to those of mice fed a healthy diet (controls) (Fig

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The adjusted Cox proportional hazards models were applied to assess the association of GLP-1 RAs with the risk of DR

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