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Evidence Considering a high K m value for L-arginine as substrate for arginase (13 mM), it has been reasoned that the main function of arginase is to limit the intracellular accumulation of L-arginine

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[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Hang Y., Wang A., Wu N

Designing future studies may require careful attention to which endpoint is primary, as that will dictate whether a lower, moderate, or higher dose is emphasised