Compared with healthy circulating neutrophils, those from patients with RA displayed a higher production of reactive oxygen species (ROS), as well as a higher expression of Fc receptors [8, 9]
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In addition, other work has stablished that Cu toxicity directly inhibits heme biosynthesis in the obligate human pathogen Neisseria gonorrheae
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In other cell populations, interaction between lactate and immune cells influences cell differentiation, immune response, immune surveillance, and sensitivity to treatment
