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Glutathione Dysregulation and the Etiology and Progression of Human Diseases. Biological Chemistry , U.S

The primary S source is sulfate, which, following uptake by specific transporters, is reduced and incorporated into the amino acids Cysteine (Cys) and Methionine, and thereafter into proteins and peptides, including the multifunctional tripeptide thiol glutathione (Takahashi et al., 2011)

Incorporation of a Single His Residue by Rational Design Enables Thiol-Ester Hydrolysis by Human Glutathione Transferase A1-1 Hederos, S., Broo, K.S., Jakobsson, E., Kleywegt, G.J., Mannervik, B., Baltzer, L

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Energy metabolism and cortical spreading depression susceptibility Cortical spreading depression (CSD) is a neurophysiological phenomenon characterized by the strong depolarization of regional neurons or glial cells, spreading along the cortex to neighboring regions at a rate of 35 mm/min, ultimately leading to inhibition of neural activity (9)

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