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notably, metformin is an FDA-approved medication, while berberine is a natural supplement

FDA-approved small molecule drugs with covalent mechanisms of action

as Cu I levels in the cell rise, two Cu I displace the single Zn II to form an S 4 Cu 2 cluster that impairs DNA binding

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Supports Workout Performance By assisting energy production, L-Carnitine may help support exercise performance and physical activity levels