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doi: 10.1016/j.chembiol.2008.02.010 13 KhareASamudre S and AroraA
In addition, less than 30% of patients remain on treatment for more than a year 6,7,8 , and treatment discontinuation typically results in rapid weight regain 4,9,10 , with the majority of this gain attributed to increases in fat mass 11,12,13
Such disturbances have been described in ASD brain tissue and support the relevance of methyl-donor pathways in ASD biology [32,33,34]
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