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In general, apoB-containing lipoproteins, such as LDL and chylomicron remnants, link to plaque buildup in the arteries (not good).[ref] Luteolin acts on HNF4, a nuclear transcription factor, in regulating the secretion of apolipoprotein B (apo B) containing lipoproteins.[ref] This means that luteolin is acting upstream of the production of cholesterol in the liver regulating the production of cholesterol

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Alternate the injection sites, especially with subcutaneous injections, to avoid irritation