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[PMC free article] [PubMed] [Google Scholar] 11.Prasad M., Jayaraman S., Eladl M.A., El-Sherbiny M., Abdelrahman M.A.E., Veeraraghavan V.P., Vengadassalapathy S., Umapathy V.R., Jaffer Hussain S.F., Krishnamoorthy K., et al

The H 2 O 2 concentration drives the redox balance in the cell from GSH toward GSSG (see Figure 1) and the increased concentrations of H 2 O 2 and GSSG can modulate many enzymes in one-carbon metabolism (see Section E)

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ED: 10 mL/kg distilled water

Astrocytes can at least temporarily switch to the glycolytic pathway to support their own energetics, and can use their glycogen pool (of which they are the sole possessors in the CNS 205,206 ) to produce lactate and support energy substrate-deprived neurones

doi: 10.1152/ajpcell.00355.2007