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The table below summarizes all four concentrations at 50 units: This is why the question "is 50 units a lot" has no universal answer

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Low energy, tiredness and brain fog that has not responded to lifestyle changes Vegetarians and vegans who do not get B12 from animal foods Patients with absorption issues such as IBS, coeliac disease or pernicious anaemia, with appropriate GP oversight Anyone on long-term metformin or proton-pump inhibitors that lower B12 absorption Older adults whose stomach acid has dropped with age Patients looking for mood, focus and recovery support alongside a balanced diet Aftercare For the first forty-eight hours

125 TianY.JiangW.GaoN.ZhangJ.ChenW.FanD.et al (2010)