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Understanding their potential disease-modifying effects on the inflamed synovium is essential to determine whether these therapies could alter the trajectory of OA rather than solely improve symptoms
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Lysosomal acid lipase deficiency an under-recognized cause of dyslipidaemia and liver dysfunction
Some evidence suggests cytotoxic antibodies, which are thought to be different from TPO Ab or TG Ab, could cause fetal hypothyroidism(57)
M.ReddyL
25, 38 As aberrations in the TP53 gene and t(4:14) translocations are seen in 15% of patients 49 and correlated with short progression-free survival and resistance to alkylating agents at relapse, 50 the ability of BSO to sensitize MM cells with this phenotype suggests that BSO+L-PAM may have clinical activity in the most aggressive forms of MM
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