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Vitamin B12, also known as cobalamin, is a water-soluble vitamin that supports DNA synthesis, red blood cell formation, and neurological function

Cisplatin (CP) is one of the most effective antineoplastic drugs for the management of several solid-organ malignancies including Hodgkins and non-Hodgkins lymphomas, sarcomas, as well as head, lung, neck, bladder, breast, testicular, ovarian, and cervical cancers (Manohar and Leung, 2018)

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Moreover, during the phase I detoxification reaction in liver cytochromes P450 enzymes, ROS are produced, such as in alcohol-induced liver damage [53]