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Oxidative and nitrosative stress and immune-inflammatory pathways in patients with myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS)

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4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid is a prospective cancer drug and has just completed a phase I dose escalation study in patients with solid tumors refractory to standard therapy ( 4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid consists of a phenylarsenoxide moiety attached by an N -acetyl linker to the cysteine thiol of reduced GSH ( Figure 3 )