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ABC News' Youri Benadjaoud contributed to this report

doi:10.1038/ki.1984.36 Rege AB, Brookins J, Fisher JW

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In cases starting with a higher dose and then continuing with a regular dose helps in maintaining consistent antibacterial effectiveness

Specifically, they act as glucagon-like peptide-1 (GLP-1) receptor agonists, enhancing insulin secretion in response to meals, suppressing glucagon release (which raises blood sugar), and slowing gastric emptying to promote a sense of fullness