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Ionizing radiation from radiation therapy also induced HIF-1 accumulation, which resulted in nuclear translocation of SLC7A11 and inhibited ferroptosis in HCC (138)

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For example, skin agingarguably the most recognizable sign of aginghas traditionally been described at the histological level, but it is now understood that these changes result from more specific failures at a cellular level, revealing new therapeutic targets with the potential to address aging at its root cause (Fig

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SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators

Cutan Ocul Toxicol 35:281286