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Design and synthesis of A PD-1 binding peptide and evaluation of its anti-tumor activity

Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria

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Cell death was quantitated as Red Object Count (per image) normalized to confluence (per image)

Chemical synthesis using solid-phase peptide synthesis (SPPS) is suitable for shorter peptides and allows for precise control over peptide structure