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Moreover, in this work, Van Pelt and Truttmann mentioned an HSP70 member of the nematodes, F44E5.4 (initially cytosolic), to manage PQC in the ER in depletion of GRP78 orthologs, at least for the clearance of mutant polyglutamine proteins

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Figure 1B shows an overview of the preclinical study design with healthy and T2DM subjects

Citation5 Both approaches offer a unique opportunity to delay the onset of age-related diseases and extend the healthspan, the period of life spent in good health