Future therapies: Scientists are developing next-generation GLP-1 drugs that may have an even greater impact on brain health
This pathway: Promotes synaptogenesis the formation of new synaptic connections between neurons Mimics BDNF activity downstream effects on neuronal survival, plasticity, and growth Enhances hippocampal function the hippocampus is critical for memory formation and retrieval Crosses the blood-brain barrier unlike BDNF itself, Dihexa is small enough to penetrate the BBB The result is enhanced neural plasticity the brain's ability to reorganize and form new connections, which underlies learning, memory, and cognitive performance
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[DOI] [PubMed] [Google Scholar] 81.Gajger I.T., Ribaric J., Skerl M.S., Vlainic J., Sikiric P
Instead, reducing protein intake may be more effective at lowering IGF-1 levels
In the meantime, the drug will remain available to PBC patients under its accelerated approval status, according to Intercept