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Pre-before-post pairing of synaptic stimulation with bursts of depolarization-evoked postsynaptic spikes induced LTP in 5 out of 10 paired inputs (Figure 2), LTD in two, and did not lead to changes in the remaining three inputs

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Whenever you avoid high lactate levels, you improve pyruvate recycling, favouring glucose resynthesis and, therefore, avoiding muscle fatigue, which is the goal

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