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Originally developed to help manage type 2 diabetes, it is now widely used to support healthy, sustainable weight loss in eligible patients

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It creates an environment where we have legalized snake oil, says Pieter Cohen, an internal medicine physician at Cambridge Health Alliance in Massachusetts who studies supplement safety

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The STEP trial programme (which primarily enrolled adults without type 2 diabetes) showed that participants with obesity achieved an average weight loss of approximately 15% of their initial body weight over 68 weeks, compared to 2.4% with placeboall participants also received lifestyle intervention