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Ozempic contains semaglutide, a synthetic version of glucagon-like peptide-1 (GLP-1), a hormone your body naturally produces after eating

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Orlistat blocks about 25% of the fat you eat from being absorbed, which can lead to significant weight loss when combined with a low-fat diet

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Moreover, the leptin surge after treatment cessation is an underestimated driver for the weight rebound, underscoring that a reduction of leptin per se (i.e., even prior to any weight loss) is a direct driver of reduced fat mass

Beyond improving glycemic control, these medications help with weight loss, quiet food noise and T1D hunger, and reduce the risk of heart and kidney disease