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Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione

Initiation of periodontal disease by bacteria is well-documented, and the end result, destruction of the alveolar bone and other connective tissues is readily observed

Consequently, TNF inhibitors, as primary biologics for managing autoimmune diseases, are naturally anticipated to be effective in treating AA

J Immunol 183 : 46014608 Fitzpatrick AM, Holguin F, Teague WG, Brown LA 2008 Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma

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The recommended protocol is once weekly for the first 3 months (intensive phase), then once every 24 weeks for maintenance