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3.7 Metformin significantly inhibits oxidative phosphorylation and glycolysis in rectal adenocarcinoma biopsies Having demonstrated metabolic modulatory effects of metformin in an in vitro model of rectal cancer, the effect of metformin treatment on the metabolic rate of treatment nave ex vivo rectal adenocarcinoma biopsies was assessed in real-time using the Seahorse XFe analyser

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These molecules then enter the Krebs cycle in the mitochondria, ultimately producing energy in the form of ATP

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You can still eat and drink whatever you want, and you can brush and floss normally to maintain healthy gums and teeth

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