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It had been suggested, based on studies looking at the expression of 17-Hydroxylase/C17-20-lyase and hydroxysteroid sulfotransferase, that sulfated steroids, such as DHEAS are unlikely to be synthesized de novo within the human hippocampus (186)

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Metabolic dysfunction (and the more severe metabolic syndrome) are exacerbated by modern lifestyle and dietary habits, leading to chronic inflammation and oxidative stress, which further degrade cell functioning

Well just see more of that if the FDA decides to turn a blind eye to compounding and marketing of these peptides