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A key extrinsic pathway component is the death receptor Fas (CD95), which, upon binding to Fas ligand (FasL/CD95L), recruits the adaptor protein FADD (Fas-associated death domain protein) and procaspase-8 to form the death-inducing signaling complex (DISC)

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Additionally, growing evidence indicates that statins may help slow the progression of fibrosis and cirrhosis and reduce the risk of liver cancer in MASLD [158-160]

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