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In breast cancer, transcription factor AP-2 gamma (TFAP2C) is an important transcription factor that regulates estrogen receptor-alpha (ER) and c-ErbB2/HER2 (Her2), which are involved in the establishment of the gene expression pattern observed in different clinical phenotypes of breast cancer [79, 80]

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Multiple forum users report that prescription-strength retinoids helped them recover, likely because tretinoin stimulates collagen synthesis through a different pathway (increasing bFGF - basic fibroblast growth factor)

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(November 2017)