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213%) while decreasing the levels of GSH ( F (3, 16) = 409.06

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Inclusion and ethics This research was conducted in collaboration with local researchers who contributed to study design, data collection, analysis, and authorship

47 Visceral fat accumulation in patients with obesity causes a number of changes (oxidative stress, activation of the RAAS and gut dysbiosis), resulting in insulin resistance, increased vascular stiffness, T2D, dyslipidaemia, hypertension, coronary atherosclerosis and, ultimately, HFpEF

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However, our study also reported significantly increased levels of Pro, Leu, and Val, as well as decreased levels of Ser and Gly, which were inconsistent with our observations