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The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )

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Safety information The most common side effects of cyanocobalamin injections include mild injection site reactions (such as redness or soreness), headache, nausea, and diarrhea

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the RDA is 2.4 g/d