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As demonstrated by Feetham CH et al., acute activation of BDNF neurons in the medial nucleus of the tractus solitarius reduces food intake and promotes fatty acid oxidation, potentially contributing to sustained weight loss (49)

Readers can follow the generic semaglutide tracker for further authorizations and consult our FAQ for background on regulatory terminology

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Improvement in mood and reduction of severe depression

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The liver fat reduction data from retatrutide trials, where more than 85% of participants achieved normal liver fat levels, has no equivalent in semaglutide literature