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Sex hormones and UV radiation have been implicated in the development of melasma (Espsito et al, 2022)

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The solution has turned cloudy or hazy after being clear at reconstitution

Diabetes is characterized by hyperglycemia, oxidative stress and abnormalities in lipid metabolism

A systematic review and meta-analysis of 10 randomized trials totaling 1,030 patients (Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome, Ingrosso, Ianiro, Ford and colleagues, Alimentary Pharmacology & Therapeutics , 2022) found peppermint oil superior to placebo for global IBS symptoms (number needed to treat = 4) and abdominal pain (number needed to treat = 7)