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In an ex-vivo human study, a closely related copper tripeptide stimulated elongation of isolated human hair follicles and the proliferation of dermal papilla cells while reducing markers of cell death, according to PubMed (Pyo et al., 2007, DOI)

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Activation of TRPV1 restored GPX4 levels, reduced lipid peroxidation, and improved cartilage integrity in both IL-1treated chondrocytes and OA mouse models ( These findings highlight the importance of considering cellular heterogeneity in ferroptosis regulation and suggest that targeting ferroptosis in a subpopulation-specific manner may enhance therapeutic precision in OA

J Neural Transm (Vienna)

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