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Brain insulin resistance may indeed play a role in the pathophysiology of cognitive disorders, and addressing this may be a mechanism through which GLP-1RAs act pro-cognitively 35

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Nodoubling doses increases nausea, vomiting, and GI discomfort without improving weight loss and can be unsafe

If youre on a GLP-1 medication Ozempic, Wegovy, Mounjaro and youve been told to add NAD+ to your protocol, youve probably encountered some version of the same pitch: NAD+ gives you the energy back that GLP-1 drugs take away

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