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It catalyzes the removal of H + ions from glucose-6-phosphate to produce 6-phosphogluconate and requires a cofactor, NADP

In the intrinsic pathway, mitochondrial membrane permeabilization allows cytochrome c to enter the cytosol, forming the apoptosome with APAF-1 and caspase-9, which then activates caspase-3, leading to nuclear fragmentation, protein degradation, and chromatin condensation [32]

Reducing frequency temporarily or applying a light, non-comedogenic moisturizer can help minimize irritation during the adjustment period

A4: Some individuals may experience mild side effects like redness or swelling at the injection site

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