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[155] Patients should be counseled that while some improvement may be noticed early in treatment, optimal therapeutic benefit may take time to develop

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Results from the OASIS 4 trial displayed that patients administered with the Wegovy pill once a day along with a reduced calorie diet and exercise achieved an average weight loss of 13.6%, compared to just 2.4% with placebo

Magnolo N, Jaenicke T, Tsianakas A, Czech W, Thai D, Pinter A, et al

Studies have found that there is an increase of phosphorylated MAP1B bound LC3 in Lurcher mice, which leads to the presence of high numbers of LC3-labeled autophagosomes in the axon terminals of PCs [81, 97]