Inconsistent dosing may trigger nausea, dizziness, or irregular appetite suppression as your body adjusts to fluctuating medication concentrations
Lancet Lond Engl 394:121130 Frias JP, Nauck MA, Van J, Benson C, Bray R, Cui X, Milicevic Z, Urva S, Haupt A, Robins DA (2020) Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: A 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens
There were no increase in thyroid cancers with DPP4 inhibitors
Q: Why is muscle support important during weight loss
Individual Health Conditions: Conditions like type 2 diabetes can exacerbate fatigue, particularly as the body adjusts to better-managed blood sugar levels
For context on how it compares to GLP-1 medications, see our phentermine vs GLP-1 comparison and guides on combining phentermine with semaglutide or phentermine with tirzepatide