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To fully realize the translational potential of GLP-1R agonists, future efforts must address gaps in implementation and integrate real-world evidence into clinical decision-making

Counterfeit products are different from compounded drugs as they are illegally manufactured, distributed, and are often contaminated with undeclared active ingredients

In clinical studies, participants received a once-daily pill, with or without food (NEJM 2023)

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When calorie intake decreases significantly, protein consumption often drops as well