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Because you're not eating as much, you may not be getting the fiber you need to bulk up stool and keep things moving smoothly, which can also lead to constipation (especially if you're also not drinking enough fluids), says Hamilton

That said, real-world results can sometimes differ due to factors such as inconsistent dose adjustments or challenges with staying on the treatment plan

Dr Jessica Atieh

Prior to the advent of GLP-1s, diet and exercise or bariatric surgeries were the main routes to weight loss for obese Americans

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